Is Heartgard Safe for Dogs?

Heartworm ailment affects pet dogs of all ages and is observed in all 50 states [1]. Heartworm is carried by mosquitoes. Just just one chunk from an contaminated mosquito can transmit this potentially fatal disease to your doggy. 

Heartgard and Heartgard Furthermore are two of the best vet-suggested heartworm disease preventives for canines. But what are the lively ingredients and is Heartgard safe for canines? 

Here’s what you want to know regarding the protection of Heartgard and Heartgard Moreover so that you can make informed conclusions for your pet dog. 

What Is Heartgard for Canines?

Heartgard is a medicine that is used to reduce heartworm condition in pet dogs. Heartgard is made up of ivermectin and only prevents heartworm disease. Heartgard In addition contains both ivermectin and pyrantel, and is supposed to protect against heartworm sickness, as effectively as take care of and control hookworms and roundworms. 

Puppies are contaminated with heartworm larvae from the chunk of an contaminated mosquito. Ivermectin prevents heartworm disease by focusing on and killing any immature heartworm larvae that might have been transmitted to your pet via mosquito bites. 

Pyrantel, the other energetic ingredient in Heartgard Furthermore, is an intestinal dewormer that kills hookworms and roundworms. Most pet parents and veterinarians prefer applying Heartgard Furthermore vs. Heartgard mainly because of the more defense in opposition to intestinal parasites that are also contagious to human beings.

Is Heartgard Harmless for Pet dogs?

Heartgard Plus for dogs

Heartgard, when properly recommended through a veterinarian, is risk-free for most canine. Your veterinarian will take several things into account when prescribing heartworm avoidance to your pet dog, like your dog’s breed, concurrent wellness conditions, and which parasites your puppy demands defense from. If your veterinarian has any issues about the security of Heartgard in your canine, they may possibly want to run some blood assessments before prescribing it. Dogs with seizures and pet dogs with kidney sickness should be evaluated by a veterinarian in advance of they are approved any heartworm prevention, which include Heartgard Plus. Your veterinarian is greatest suited to ascertain the best heartworm avoidance for your pet dog. If your pet dog has liver illness, kidney disorder, or a seizure dysfunction, chat with your veterinarian about choices for heartworm avoidance.

Heartgard Furthermore has shown to be pretty protected when the encouraged dose is administered to most puppies, including expecting dogs, breeding dogs, stud pet dogs, and puppies who are older than 6 months of age.

As talked about before, ivermectin is a single of two active ingredients in Heartgard Furthermore. Ivermectin is protected for most dogs when it is employed at the suitable dosage and underneath the supervision of a certified veterinarian. Even so, not all puppies can acquire ivermectin. Some herding doggy breeds are a lot more sensitive to ivermectin owing to a mutation in their MDR1 gene. This can include:

  • Collie
  • Border Collie
  • Australian Shepherd
  • Mini Aussie
  • Outdated English Sheepdog
  • Sheltie
  • Combined breed with herding canine

In puppies who have the MDR1 mutation, ivermectin can cross the blood-mind barrier and cause significant mind hurt that can be deadly. There is a very simple genetic check accessible to look at if puppies have the mutation that triggers sensitivity to ivermectin. In typical, the dosage of ivermectin contained in heartworm prevention is much beneath the poisonous dose and regarded as risk-free even in delicate breeds. However, if you have considerations, communicate to your veterinarian. 

Heartgard for Puppies: Precautions to Consider

Heartgard In addition has been prescribed to thousands and thousands of canine and used safely and securely without the need of any side results. The large the vast majority of dogs who acquire Heartgard Plus do not expertise side consequences. 

Can Heartgard Plus induce diarrhea in puppies? Clinical trials screening the basic safety of Heartgard in pet dogs showed that about 1 percent of canines experienced vomiting or diarrhea following administration [2]. Pet dad and mom have noted some adverse results after offering Heartgard Moreover to their doggy. Heartgard In addition for pet dogs aspect results documented in some canines contain:

  • Small power
  • Vomiting
  • Diarrhea
  • Dilated pupils
  • Incoordination
  • Confusion
  • Seizures
  • Drooling

If you observe any facet effects soon after supplying Heartgard As well as to your dog, check with with your area veterinary, regional emergency clinic, or the Pet Poison Hotline as soon as attainable. Most facet outcomes will solve in just a day or two, but some may possibly call for unexpected emergency treatment.

Heartgard must only be applied in canine who have tested damaging for heartworm illness. Heartgard items are not effective against grownup heartworms. Hence, canines who are infected will have to be taken care of to remove adult heartworms and microfilariae that are circulating in the blood prior to working with Heartgard as every month heartworm prevention [3]. 

The basic safety of Heartgard Additionally has also been analyzed and demonstrated to be secure in dogs when specified at the exact same time as lots of solutions, which includes:

  • Flea collars
  • Medicated and unmedicated shampoos
  • Antibiotics
  • Vaccines
  • Steroids 
  • Parasite medication

The ingredients in Heartgard can, even so, have unfavorable interactions with certain medications and herbs, so be sure to tell your veterinarian about anything you are giving your dog ahead of they are recommended Heartgard, which include vitamins, herbs, and dietary supplements. 

Some dogs who gobble their treats total can be at risk for choking on the chewable tablets. If this is the situation for your canine, break up the pill ahead of administering it.

It is achievable to overdose a canine on Heartgard Furthermore, so never ever double up doses to “catch up” or give your dog far more than the approved amount of money. If your puppy accidentally overdoses on Heartgard In addition, call your local veterinarian, the unexpected emergency clinic, or the Pet Poison Hotline quickly for support. If you pass up a dose of Heartgard Additionally and it is longer than 30 times considering the fact that the final dose was given, simply call your veterinarian for tips.

In normal, Heartgard Additionally is risk-free and nicely tolerated by most canine, and since its introduction has saved a great number of lives from heartworm disorder. In addition, Heartgard Plus treats and controls intestinal parasites in pet dogs that are also public health concerns for individuals. Heartgard As well as should really not be applied in all canines, nonetheless, and need to only be approved and administered underneath the supervision of a accredited veterinarian. 


  1. Heartworm Incidence Map. American Heartworm Modern society. 2022. Retrieved from:
  2. Heartgard Furthermore prescribing details. Retrieved from: well as_PI.pdf
  3. Heartworm Lifestyle Cycle illustration. American Heartworm Society. Retrieved from

The post Is Heartgard Safe for Canine? appeared 1st on Excellent Pet Treatment.