5 Dog Incontinence Medications That Could Help

Have you ever noticed drops of doggy urine in your home or on your dog’s bedding? It could be thanks to incontinence. Urinary incontinence in puppies is a clinical affliction that results in a canine to leak urine. This frequent concern is approximated to impact 5–20 percent of spayed dogs [1] and around 1 percent of male canine [2], but canine incontinence prescription drugs are minimal. 

On the other hand, if your pet is diagnosed with urinary incontinence, there are some accessible medicine and supplements that may aid. In this article are some possibilities to discuss with your veterinarian.   

Why Your Pet May possibly Want a Pet dog Incontinence Medicine

Your veterinarian will prescribe incontinence treatment the two for your pet’s gain and your advantage. Maintain in brain that we are specially talking about pet dogs who leak urine with no awareness or command, not puppies who excessively urinate due to a condition like diabetes or who come to feel the urge to urinate regularly due to anything like a urinary tract an infection (UTI).

Your female puppy leaking urine is additional most likely to get urine scalding about her vulva or to excessively lick at her vulva, which may outcome in a UTI. If you put a diaper on an incontinent pet dog (male or woman), they are additional probably to get urine scalding, skin bacterial infections, and UTIs. Urinary incontinence remedies for canine can help avoid these wellness difficulties.

As much as we really like our animals, we also never want smaller puddles of urine on the carpets and home furnishings. Managing urinary incontinence will assist preserve your residence cleaner (and smelling improved, ideally).

Kinds of Incontinence Prescription drugs for Pet dogs

Prescription drugs for urinary incontinence can assistance with incontinence that is thanks to sphincter incompetence. Nevertheless, canine incontinence prescription drugs are unlikely to assistance animals with urinary incontinence owing to neurologic health conditions (spinal harm or congenital malformations like ectopic ureters).

In some scenarios, your veterinarian may possibly advise much more than 1 treatment to optimize management of urinary incontinence. 

Hormonal Remedies

Most situations of urinary incontinence in canines arise in spayed women. There is a sphincter about the urethra (tube from bladder that takes urine out of the system) which retains urine from leaking. In spayed dogs, this sphincter may possibly come to be incompetent, meaning it doesn’t preserve all the urine in.

For these canine, hormonal therapies are advised. These prescription drugs change the motion of estradiol, a normal estrogen that decreases in focus right after spaying.

In male canines, testosterone injections may possibly address urinary incontinence. This is considerably less successful than hormone therapy for female canines, and it may possibly result in unwanted behaviors (marking and humping). This is not routinely advised by veterinarians.

Non-Hormonal Medicines

The principal class of non-hormonal medicines for urinary incontinence is alpha-adrenergic agonists. These remedies act on the receptors of the urethral sphincter in canine to raise urethral tone. The tightening of the sphincter increases the capacity of the bladder to hold urine.

The antidepressant treatment imipramine could also enable with urethral tone although possibly calming the bladder.

In some situations, anti-panic prescription drugs and muscle relaxants may perhaps be prescribed to aid with bladder rest, specifically in male dogs who are unresponsive to the regular therapies.


Nutritional supplements are not routinely prescribed for urinary incontinence, but there are a few choices which might advertise urinary tract overall health when employed in conjunction with other health-related therapies.

5 Doggy Incontinence Remedies and Dietary supplements 

Incurin (Estriol)

Incurin for dog urinary incontinence

Incurin is the brand name for the energetic ingredient estriol. Estriol is an estrogen that can address estrogen-responsive urethral sphincter mechanism incompetence (USMI) in spayed females, the most common form of urinary incontinence viewed in pet dogs. The Fda-authorized treatment enhances urethral sphincter tone.

An vital note is that Incurin is not dosed by bodyweight. All pet dogs will at first obtain 2 mg by mouth as soon as for each working day. If successful, the dose is systematically tapered to the lowest productive dose. You need to comply with your veterinarian’s directions precisely to make certain you are tapering this treatment properly.

Incurin and its active ingredient estriol is only a procedure possibility in spayed female puppies who are about a calendar year old. The most popular side consequences include gastrointestinal challenges like vomiting or estrogen-similar alterations like a swollen vulva. Estrogens carry the possibility of bone marrow toxicity, but this is unheard of when following your veterinarian’s dosing recommendations. Caution is encouraged in puppies with liver disorder or who are on steroids like prednisone.

Proin (Phenylpropanolamine HCl)

Proin for urinary incontinence in dogs

Proin is a pet incontinence medication manufactured from the active component phenylpropanolamine HCL. Phenylpropanolamine is an alpha-adrenergic agonist utilised to treat pet dogs with urinary incontinence due to lessened muscle tone in the urethral sphincter. By stimulating alpha-adrenergic receptors in the urethral sphincter, the medication raises urethral sphincter tone, preventing leakage from the bladder.

There are a number of formulations readily available, so some dogs will obtain phenylpropanolamine by mouth at the time every day and others will get the medication two times everyday. Some instances may perhaps demand administration each and every 8 several hours.

Phenylpropanolamine is an choice the two for female and male puppies. Caution is encouraged in animals with heart disorder, glaucoma, enlarged prostate, hyperthyroidism, diabetic issues, Cushing’s illness, liver disorder, kidney ailment, and significant blood force.

Detrimental aspect consequences could contain greater blood stress, coronary heart rhythm abnormalities, vomiting and decline of appetite, panic and irritability, diarrhea, and greater thirst. These are much more very likely at higher doses or with overdose.

Proin is categorized as a controlled material in some states because of to probable abuse as a precursor to methamphetamine. More verification of the prescription with your veterinarian might be required. If you stay in a state where by Proin is managed, there may perhaps be specific guidance for destruction of unused treatment. Be sure to verify with your veterinarian.

Imipramine Hydrochloride

imipramine medication for dogs

Imipramine is a tricyclic antidepressant that indirectly stimulates alpha-adrenergic receptors, growing tone in the urethral sphincter. The treatment may possibly also assist with bladder leisure. In human beings, this medication is frequently utilised to lower bed-wetting in little ones.

Imipramine is supplied by mouth 2 times everyday. Controlled studies regarding efficacy of imipramine for urinary incontinence in puppies are at present missing.

This treatment is an selection for both of those male and female pet dogs. The medication need to not be utilized in puppies who are on one more kind of antidepressant referred to as a monoamine oxidase inhibitor (MAOI), these kinds of as selegiline. Warning is also advised in pet dogs with seizure ailments, heart condition, thyroid illness, kidney illness, liver ailment, and glaucoma.

Adverse side results consist of constipation, hyperexcitability, tremors, seizures, vomiting, diarrhea, and sedation.

VetriScience Bladder Strength Dietary supplement

VetriScience bladder supplement for dogs

VetriScience Bladder Strength Nutritional supplement aims to strengthen bladder regulate, reinforce bladder muscles, make improvements to bladder emptying, and prevent urinary tract bacterial infections. Energetic elements include things like pumpkin seed powder, Rehmannia glutinosa root powder, wild yam extract, soy protein extract, corn silk powder, saw palmetto extract, olive leaf extract, and vitamin B6.

The complement is given by mouth possibly the moment or twice every day.

The supplement is typically aimed in the direction of spayed female dogs and senior puppies but is an possibility for both male and woman animals. With any medication or nutritional supplement given by mouth, abdomen upset that could outcome in vomiting, diarrhea, and reduction of urge for food is achievable.

In the United States, nutritional supplements are regulated by the Food and Drug Administration (Fda) as foods, not as prescription drugs. This indicates there is no regulatory assurance relating to the top quality or efficacy of elements. VetriScience products do have the excellent seal of the National Animal Complement Council (NASC) which identifies solutions from organizations committed to developing high quality complement solutions.

PRN Pharmacal CranMate Chew Tabs

CranMate supplement for dogs

CranMate is a complement for supporting a healthful urinary tract. This dietary supplement is not automatically heading to make improvements to urinary incontinence but may well aid the urinary tract of puppies who are on extended-time period medications for incontinence, which includes those who are inclined to urinary tract infections. CranMate is built with American Cranberry purified fruit extract. Other active ingredients include things like sorbitol, dicalcium phosphate, microcrystalline cellulose, whey powder, liver powder, soy protein concentrate, iron oxide, silicon dioxide, and magnesium stearate.

The nutritional supplement is offered by mouth as soon as everyday but might be supplied two times daily through UTI occurrence. 

The complement is an possibility for both equally male and woman pet dogs. With any medicine or health supplement given by mouth, tummy upset that could result in vomiting, diarrhea, and decline of hunger is achievable.

As beforehand talked about with other doggy urinary supplements, there is no regulatory warranty relating to the good quality or efficacy of substances. Having said that, PRN Pharmacal follows Existing Good Production Techniques (CGMP) and benchmarks. 

Other Medication Selections for Urinary Leaking in Pet dogs

In some situations, specially for male pet dogs who aren’t responding to the usual medicine solutions for urinary incontinence, your veterinarian may propose medicines geared in direction of incomplete bladder emptying. These canine may perhaps truly have overflow incontinence somewhat than concerns with their urethral sphincter. 

Medicines that enable with muscle peace – these types of as prazosin or methocarbamol – may perhaps be advisable in these instances. Anti-stress remedies like diazepam may also be prescribed. 

If your pet is not responding to the standard prescription drugs, make absolutely sure to discuss with your veterinarian about bladder-emptying issues.

Pet Incontinence Drugs: Suggestions and Safety

Make guaranteed to talk about any pre-current circumstances with your veterinarian prior to starting up a prescription incontinence treatment, especially if your pet has coronary heart, kidney, liver, thyroid, or eye issues.

If your dog experiences sizeable facet outcomes, get hold of your veterinarian in advance of continuing the treatment.

Some of these remedies, this sort of as Proin, are intended to style great to your pet. This suggests there is a possibility that your pet dog may possibly make your mind up the treatment is a wonderful address and accidentally overdose if they get obtain to the bottle. Preserve these prescription drugs out of access of small children and pets.

If your dog’s incontinence does not boost irrespective of medicines, it is feasible that they have a different less common induce of urinary incontinence, so stick to up with your veterinarian for extra diagnostics. Dogs beneath a person calendar year previous with incontinence really should have congenital flaws of the urinary tract ruled out right before setting up prescription drugs.


  1. Forsee, Kara M., Garrett J. Davis, Emily E. Mouat, Katharine R. Salmeri, and Richard P. Bastian. “Evaluation of the prevalence of urinary incontinence in spayed woman dogs: 566 circumstances (2003–2008)”. Journal of the American Veterinary Medical Association 242.7 (2013): 959-962. doi.org/10.2460/javma.242.7.959. Website. 12 Feb. 2024.
  2. Pegram, C et al. “Associations concerning neutering and early-onset urinary incontinence in Uk bitches less than key veterinary treatment.” The Journal of small animal follow vol. 60,12 (2019): 723-733. doi:10.1111/jsap.13072